The comparison of clonidine and dexmedetomidine as an adjuvant to 0.5% bupivacaine in epidural anaesthesia for lower limb surgeries

Background and Objectives: Epidural anesthesia is a popular technique for providing lower limb surgeries. Dexmedetomidine Clonidine are known to enhance the effect of local anaesthetics. The purpose this study was compare impact dexmedetomidine clonidine on onset duration epidural anaesthesia using bupivacaine. Methods: After IEC approval, prospective, randomized, double blinded conducted 60 ASA I II adult patients undergoing surgeries under anaesthesia. Patients were randomly divided into Group A receiving 0.5% isobaric bupivacaine 15 ml with 1 μg/kg B 2 epidurally. Onset sensory motor blocks, analgesia, sedation, adverse effects assessed.Results: block significantly faster in Gr compared (p< 0.05). more D M. Mean arterial pressures comparable between groups intraoperative period. However, sedation scores better than clonidine. No other event observed.Conclusion: combination (0.5%) hastened block, prolonged when used epidural, without producing any events.